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starts from glutamic acid --> g-(P)glutamate --> gluamate semialdehyde --> pyrrolidine2-carboxylate --> proline
or, from ornthine --> gluamate semialdehyde --> pyrrolidine2-carboxylate --> proline; but this normally goes the other way aroudn to make ornithine
certain genetic diseases of the first (major) pathway do cause the secodn to turn around and be used to make proline, but the loss of ornithin causes Nitrogen imbalances and a lot of problems.
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