You need to burn the iso on to a cd/dvd using software which allows you to burn iso's. You can also mount the iso using software like daemon tools which would circumvent the need to burn the iso onto cd/dvd.
You can use this site:
http://gameolosophy.com/games/sports/total-club-manager/how-to-mount-image-files-iso-file/
Burn it using NERO to a CD/DVD. Now you can use it. If you are using an ISO file of game then use a PlayStation emulator
To convert an MDF file to an ISO file, you can use software like PowerISO, MagicISO, or AnyToISO. Simply open the MDF file with the chosen program and select the option to save or convert it as an ISO file. After conversion, you will have an ISO file that can be used for mounting or burning to a disc.
You need to use a piece of software capable of understanding an ISO file, or burn the file to a disk. You can use Gizmo for Windows, both the 32- and 64-bit, from here: arainia.com/software/gizmo/download.html. The latest versions of Windows, Linux, and Mac OS will allow you to burn the ISO file to a disk; once you've done so, you can use it as a regular disk. Linux allows an ISO to be mounted directly into the root file system using the "mount" command.
In order to use ISO file...u must use the programme Nero or Roxio..this allow these ISO files to be burn into the directed path that have been selected.
Use a program such as Daemon Tools to mount the ISO as a CD
use deamon tools
To convert an ISO file to an IPA file, you typically need to extract the contents of the ISO file first, as ISO files are disk images that may contain various file types. After extracting, locate the app files within the ISO, and then use a tool like Xcode or a third-party application to package the necessary components into an IPA format. Ensure that the app meets all requirements for iOS packaging, such as including a valid Info.plist file. Finally, save the output as an IPA file.
DVDs primarily use the UDF file system, although it is possible to use the ISO 9660 file system as well.
An ISO image is an archive file (also known as a disc image) of an optical disc in a format defined by the International Organization for Standardization (ISO). ISO file can not be played on a media player unless you use some other software mount the disc and then run the content (if possible) just like a CD.
I haven't tested this but try converting the software into an iso file then use magic iso
You can not edit games on a xbox 360 with a ISO file format. Even if you did edit the ISO file, you will need to mod your xbox to play a ISO file.
To check the integrity of the an ISO file you will need to open command prompt. Once in command prompt type in: c:\> fciv , and the iso file name.