CMT decreases the ability of these nerves to carry motor commands to muscles, especially those furthest from the spinal cord located in the feet and hands. As a result, the muscles connected to these nerves eventually weaken
CMT is caused by mutations in genes that produce proteins involved in the structure and function of either the peripheral nerve axon or the myelin sheath. Although different proteins are abnormal in different forms of CMT disease, all of the mutations affect the normal function of the peripheral nerves. The gene mutations in CMT disease are usually inherited.
Jean- Martin- Charcot, Pierre Marie, and Howard Henry Tooth all discovered this disease
Mutations in several genes cause the various types of CMT to occur. The most common form of the disorder, CMT1A, is caused by duplication in the peripheral myelin protein 22 (PMP22) gene.
Yes it is
It is Dominant
Yes it is
It is Dominant
They require therapy dogs since Charcot-Marie-Tooth disease has no cure and needs physical and occupational therapy.
Symptoms of Charcot Marie Tooth disease are lack of muscle, high arches in your feet and claw toes. Other diseases should be ruled out before this is locked in as a diagnosis.
X-linked Charcot-Marie-Tooth disease (CMTX) is caused by a defect in connexin 32. This protein forms connections between adjacent cells, allowing ions to flow between them.
Charcot-Marie-Tooth disease is an inherited disease. Since it does not have a cure, physical therapy is required. Therefore kids with this disease need to get a guide dogs to help them.
X-linked Charcot-Marie-Tooth disease (CMTX) is caused by a defect in connexin 32. This protein forms connections between adjacent cells, allowing ions to flow between them.