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How can a mutation in a DNA base sequence cause a change in protein?
Wiki User
∙ 6y ago
dna in a cell needs protein and chromosomes.
Elroy Murazik
Tyree West
DNA base sequences determine the protein.
So if the sequence changes, then the protein can too.
Wiki User
∙ 13y agoSimple analogy. Let us say your word processor started substituting p for a. Your sentence back at you. Remember DNA is the template for mRNA which is protein making instructions.
Whpt do DNP mutptpions hpve with pmino pcid chpnges in protein?
See?
Wiki User
∙ 15y agoIn order to answer this question, it is important to first consider the central dogma of molecular Biology - a rule which describes the flow of information at the molecular level. Information flow: DNA--> RNA--> Protein This means the final protein sequence (in terms of amino acids) is largely influenced by the DNA sequence (in terms of nucleotides) When there is a DNA mutation, the mutation is transcribed to RNA. Since the RNA sequence is used during the process of translation (protein synthesis), changes in DNA bases will be reflected as differences in codons on RNA. This will result in the insertion of abnormal amino acids and and causes a difference in amino acid changes.
Wiki User
∙ 10y agoThe function of a protein is determined by the sequence of amino acids in the protein. A genetic mutation can cause a change in the sequence of nitrogen bases in the DNA. This could cause an error in the sequence of amino acids in a protein, which can cause the protein to function improperly or not at all.
Wiki User
∙ 11y agoA DNA mutation affects proteins because it causes a random change in the sequence of nucleotides in DNA . Which this causes dramatic effects on the cell's structure or function.
Wiki User
∙ 12y agoDNA base sequences determine the protein.
So if the sequence changes, then the protein can too.
Wiki User
∙ 12y agonothing idfk lol
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How can a mutation in DNA base sequence cause a change in a protein?
dna in a cell needs protein and chromosomes.
What is a permanent change in the DNA sequence of a gene?
Basically change in the DNA sequence of a gene is associated with change in the nucleotide sequence which may result in Mutation and may cause loss of function of that particular mutated gene.
What would Translation of the DNA sequence AAGCTGGGA would result in?
This would result in a frameshift mutation. This would cause the protein, after translation, to be truncated and would most likely be non-functional. This is due to a change in the amino acid sequence and would stop the protein from forming the correct secondary and tertiary structures due to a change in the electrostatic/ hydrophobic/ h-bonding etc. parameters of the protein
If one of the nitrogen bases were replaced by a different base what effect might that have on protein synthesis?
It depends. Because many amino acids have more than one codon, it may not affect the protein at all. However, if it does change the amino acid sequence, it could cause a change in the three-dimensional structure of the protein, resulting in a mutation.
Can a change in a nucleotide cause a disease?
By changing a gene's instructions for making a protein, a mutation can cause the protein to malfunction or to be missing entirely. When a mutation alters a protein that plays a critical role in the body, it can disrupt normal development or cause a medical condition. A condition caused by mutations in one or more genes is called a genetic disorder. So, yes.
How can a mutation in a base sequence cause a change in a protein?
dna in a cell needs protein and chromosomes.
How can a mutation in a DNA bases sequence cause a change in a protein?
dna in a cell needs protein and chromosomes.
How can a mutation in a DNA base sequence cause change in a protein?
dna in a cell needs protein and chromosomes.
How can a mutation in DNA base sequence cause a change in a protein?
dna in a cell needs protein and chromosomes.
When a nitrogenous base is inserted or delete how does that affect the amino acid sequence?
The amino acid sequence is shifted, and this kind of mutation is called a frame shift mutation. All of the amino acid sequence after the mutation will be changed, which will cause a change in shape of the protein, which will then probably result in a nonfunctional protein, since the shape of a protein determines its function.
How do mutations affect translations?
A frameshift mutation may cause a change in the codon sequence, specifically the 3-base sequence which is responsible for coding a specific amino acid. A different protein, a non-functional one, or no protein at all may be the result of this change.
Why does a detetion mutation usually cause more defect during protein synthesis than point mutation?
Mutation usually causes the entire base sequence to defect. This usually happens during the protein synthesis.
In your own words write a definition for the word mutation?
mutation: a change in the sequence of DNA to cause a unusal trait
How would a protein be changed if a mutation caused a base to be added?
A mutation in which an extra nitrogen base is added is called a frameshift mutation. The rest of the sequence after the mutation will code for different amino acids, which will result in the alteration of the protein. Frameshift mutations cause severe genetic disorders.
WhIch best describes the initial change cause by a DNA mutation?
a chnge in the sequence of base pairs
A change in the base subunit sequence during DNA replication can result in?
Many times a change in the base sequence during DNA replication will cause a mutation but if it is the 3rd base often there will be no mutation . It will often give the same protein. The term is genetic "wobble" and is seen when mRNA and tRNA match do not match at the third base.
A change in the genetic material of a cell is called?
Cancer- certain mutations (changes) in a cell's genetic material may cause that cell to reproduce with out control.
