How does a ferret protect itself?

Answer 1

The three to five little venom sacks under the ferret's tail rapidly enlarge and if the threat doesn't relent they shoot up to a quart of noxious-smelling neurotoxic venom right into the predator's eyes, killing them instantly.

Answer 2

Domestic ferrets don't have any natural predators since they are domesticated and have lost all instinct to protect themselves from any predators. Domestic ferrets don't normally have a fear of humans, dogs or cats. But a ferret that has been abused or not properly socialized (not used to being around humans) would protect itself by biting - called a "fear biter" they bite humans out of fear.