The sickle cells can block the flow of blood through vessels resulting in lung tissue damage (acute chest syndrome), pain episodes (arms, legs, chest and abdomen), stroke and priapism (painful prolonged erection). It also causes damage to most organs including the spleen, kidneys and liver. Damage to the spleen makes sickle cell disease patients, especially young children, easily overwhelmed by certain bacterial infections. All The above mentiond causes will appeare if the patient not get proper medication
It depends on what type. SC and SS patients have it bad they can not participate in sports and always have to be an an appropriate temp. they have to CONSTANTLY drink water and get alot of rest .people with the trait don't really go through anything maybe alittle pain here or there every once in a blue moon but it is VERY easy to shake of no real pain occurs. SC patients have it hard but they don't have it nearly as hard as SS patients. SS patient SS are cut short because it is very hard to control SC life span is cut to short but can be if they don't take care of themselves. a SS patient that doesn't take care of themselves are SURE to die a VERY early death. there is no good cure the only possible cure is to get new bone marrow which isn't advised because there is a higher chance that you will die than anything else.
Sometimes, people wouldn't like living with Sickle-Cell disease. I, personally, have a friend who has Sickle Cell Leukemia, and he's been suffering with it his entire life. Some of the symptoms are:
Dizziness
Headaches
Coldness in the Hands and feet
Jaundice (a yellowish color of the skin or whites of the eyes)
Paler than normal skin or mucous membranes (the tissue that lines your nose, mouth, and other organs & body cavities).
So yes, living with Sickle-Cell Disease isn't all that great you guys.
There are two versions of sickle cell: sickle cell disease (which is less severe) and sickle cell anemia (which is more severe). Sickle cell disease is caused by inheritance of one allele for sickle-shaped red blood cells and often has moderate effects on a person's health. Individuals with sickle cell disease may be exercise intolerant (they get short of breath and tired faster than others), have circulatory issues that typically manifests in the capillary beds and in general they have to be a little more careful about injuries and infections because their blood cells are not all normally shaped.
Sickle cell anemia is caused by inheritance of two alleles for sickle-shaped red blood cells and can have severe effects on a person's health. Individuals with sickle cell anemia are generally exercise intolerant - they can work out some, but have to pace themselves to not use too much oxygen too fast, have true anemia in which their blood doesn't transport enough oxygen and typically have damage to their capillary beds resulting in poor circulation in the distal limbs and some organs.
No. Its hereditary
The person is homozygous for the trait
Describe the effect that sickle cell anemia has on the sedimentation rate!
blood
yes it does
it is safe to marry a person with sickle cell, provided that you are not a career of the trait.
A person can only inherit sickle-cell genes if some of their ancestors came from certain regions in Africa where the inhabitants carry sickle-cell genes. A person with one sickle-cell gene has sickle-cell trait, a milder problem. If both father and mother pass on sickle-cell genes, the child, with two genes, will have sickle-cell disease.
A person with one sickle cell is a "carrier". This means that they have the dormant cell in their genetic composition, and if combined with another with the "carrier" gene, they run the high risk on concieving a child with the blood disease-one who has two sickle cells. A person with two sickle cells, has the sickle cell disease and are carriers(The gene is not dormant but active). Hope this simplifies and explains it for you.
Malaria is common in topical ad subtropical zones. The malaria has selected the people with sickle cell anaemia. Although person with sickle cell anemia can have malaria, the carrier, or the person with sickle cell trait is resistant to malaria.
It is important to note that sickle-cell anemia comes in two forms. The homozygous sickle-cell anemia and the heterozygous sickle-cell trait. The difference between the two is that sickle-cell anemia has a high rate death rate at a young age (20~), and the sickle-cell trait is nearly asymptomatic.In regions such as North America, sickle-cell anemia would be selected against and would eventually leave the gene pool. The sickle-cell trait on the other hand, has little effect on the fitness of the organism, and as such will remain in the gene pool.In malaria endemic regions such as sub-Sahara Africa, sickle-cell anemia provides very high levels of immunity to malaria and the sickle-cell trait provides a slightly lesser level of immunity. Both forms of sickle-cell will increase the organisms fitness and as such, it will remain in the gene pool. Further on, the sickle-cell trait has greater fitness than sickle-cell anemia, hence, the sickle-cell trait will be selected as the fittest allele.If s is the sickle-cell allele and S is a normal allele;The relative fitness in malaria endemic regions;Ss > ss > SSSickle-cell trait > Sickle-cell anemia > NormalThe relative fitness in non-malaria endemic regions;SS > Ss > ssNormal > Sickle-cell trait > Sickle-cell anemia
If a person does not carry the Sickle cell trait and they marry some one with the trait. The child that comes from that relationship can never have sickle cell disease, however that child has a chance of having the sickle trait.
0mm
The person is homozygous for the trait