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Sickle-Cell Disease

Sickle-cell disease is a genetic blood disorder wherein the red blood cells are irregularly shaped due to the blood’s lowered oxygen tension. This irregularity may result in chronic anemia, serious infections, painful conditions, damage to organs and death.

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Is sickle cell anemia a point mutation?

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An example of point-mutation is sickle-cell anemia. Sickle-cell disease is hereditary.

What do people affected with the sickle cell suffer with?

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Peope with sickle cell disease suffer from pain crisis in arms,legs or ,chest. Well at least my daughter do. It is painful and she has to be admitted to hospital and receive morphine and. Iv fluids to relieve pain.

How can sickle cell be prevented?

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once youdidn't get it from birth, then it is not possible to get it when you grown up, but if you want to protect your future children not get the disease than it is better not to married from sickle cell disease man

If you mother and father are both sickle cell carriers what are the chances that you will not have the trait?

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It is impossible to predict what will happen with one person!

In a population of 2,000 people, 1,000 women have sickle cell trait and 1,000 men do not. They marry. Each couple has 2 children. 1,000 children will have sickle cell trait and 1,000 children will not.

In a population of 2,000 people, 1,000 women have sickle cell trait and 1,000 men have sickle cell trait. They marry. Each couple has 2 children. 1,000 children will have sickle cell trait, 500 children will not, and 500 children will have sickle cell anemia.

No one knows which of those parents will produce which children. No one knows how to predict how your children will turn out.

Why cant people with sickle cell do a lot of exercise?

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Exercising cost lot of energy.So Oxygen requirement increase.People with sickle cells, do not have normal number of blood cells to carry Oxygen.So energy production would not be sufficient.

What are the dangers of alcohol abuse and sickle cell trait?

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People who have sickle cell should try to avoid consuming alcohol if at all possible. This is because sickle cell causes the patient to become dehydrated in the first place, so drinking alcohol would only exacerbate the problem.

Is sickle cell an dominant or recessive?

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Sickle cell anemia is an autosomal recessive disorder. It can result from two carriers having a child together.

What component of blood is impacted by sickle cell anemia?

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Red Blood Cells. It is called

sickle cell because some of the red blood cells

are long and shaped like sickles. Although sickle

cell disease primarily affects African Americans,

it is also found in Hispanics, Italians, Greeks and

people of Mediterranean descent.

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Can sickle cell anemia cause pneumonia?

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no it dose not sickle cell anemia causes death only if African Americans

Is it safe for someone with sickle cell to have a baby?

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Answer

As you already must know Sickle Cell disease is genetic, but the GOOD NEWS is there is no known risk that babies may develop sickle cell disease.

It's a good idea to first check with a genetic specialist and make your decision from there.

Good luck!


Will a tattoo affect sickle cell disease?

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No, tattoos will not effect the disease. Just be sure to take your regular antibiotics if needed to prevent any infections.

What is the common name for sickle cell anemia?

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It is a genetic disorder.

However...

It is also a protection against malaria.

For example, if a person were born in an area where malaria is present, he or she would likely die from the disease, unless he or she inherited 1 sickle cell gene.

Malaria viruses reproduce in the red blood cells. The parent virus invades a cell, and uses the cell as a host to grow more viruses.

With 1 sickle cell gene, malaria viruses that invade a red cell are quickly destroyed, since the red cell collapses, preventing the virus from reproducing.

But with 2 sickle cell genes, red cells collapse too easily; just a bruise can cause someone to become anemic when too many red cells collapse.

In the real world, people with no sickle cell genes died from malaria. People with 1 sickle cell gene survived. People with 2 sickle cell genes died from sickle cell anemia.

It was natures way of assuring that at least half of the population survive, but it is certainly a difficult thing to live with today, now that we can more easily treat malaria.

Is sickle cell disease more common in boys or girls?

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The incidence of sickle cell disease is equal in both men and women.

However, it is believed that men who have the disease experience worse symptoms than women with the disease.

A possible reason for this is the role of oestrogen in the female body. Oestrogen helps stimulate the production of nitric oxide. Scientists believe that nitric oxide has a key role to play in reducing the symptoms of a sickle cell crisis as it dilates blood vessels, giving the sickle shaped cells more room to pass through the vessels, preventing blockages which is the cause of sickle cell crisis.

Could the same genetic condition that causes sickle cell anemia can also protect against any other diseases?

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A single sickle-cell gene protects against malaria. Two sickle-cell genes produce sickle-cell disease.

Is sickle-cell disease a result of a translocation?

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No. It arises due to point mutations (like A -> T).

Do you have to be born with sickle cell anemia?

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If you were not born with this condition then you will not develop it during your life.

The condition is generally inherited as it is a genetic mutation. However, it is possible that the mutation could spontaneously happen in any baby.

The reason why this (sometimes fatal) condition has persisted in certain African populations is because it imparts a resistance to malaria.

If malaria were eliminated how might the frequency of the sickle-cell allele change over time?

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Since people with the sickle cell allele trait are resistent to malaria, if malaria were eliminated there would be no change in the frequncy of sickle cell allele. This is because the presense of malaria does not have an affect on patients with the sickle cell allele trait.

What are the uses of a sickle?

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Sickle is used for harvesting.

Which form of anemia is a genetic disorder?

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It sounds like you are looking for Sickle Cell Anemia.