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Sickle cell anemia primarily affects red blood cells, which contain hemoglobin, a protein found in the cytoplasm of these cells rather than in a specific organelle. The disorder is caused by a mutation in the gene that encodes the beta-globin chain of hemoglobin, leading to the production of abnormal hemoglobin known as hemoglobin S. This abnormality causes red blood cells to assume a sickle shape, which can obstruct blood flow and lead to various complications. While the endoplasmic reticulum and ribosomes are involved in protein synthesis, they are not specifically associated with sickle cell anemia itself.

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AnswerBot

1d ago

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