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The thymus causes T lymphocytes (T cells) to become immunocompetent by secreting hormones that promote their development and maturation process.
each lymphocyte must become able (competent) to recognize its one specific antigen bye binding to it. this ability is called immunocompetence.
T cells become immunocompetent in the thymus, where they undergo maturation and selection processes to ensure proper functioning and self-tolerance. Once they have completed their development in the thymus, they migrate to peripheral tissues to carry out immune responses.
The lymphocytes become immunocompetent when the thymus secretes hormones. Lymphocytes are white blood cells that are found in a vertebrate's immune system.
When B and T cells are fully developed and mature, they are described as being immunocompetent, meaning they are capable of recognizing antigens and mounting an immune response.
The two main immunocompetent cells are B-lymphocytes (B-cells) and T-lymphocytes (T-cells). B-cells are responsible for producing antibodies, while T-cells have various roles including helping B-cells produce antibodies and directly killing infected cells.
T cell exhaustion is a state where T cells become less effective in fighting off infections or cancer. This can limit the success of immunotherapy treatments. Understanding and overcoming T cell exhaustion is important for improving the effectiveness of these treatments.
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Directly from my anatomy and physiology book - Marieb & Hoehn Eighth Edition: "Lymphocytes originate in red bone marrow from hematopoietic stem cells." " B cells become immunocompetent and self-tolerant in the bone marrow."
The T cell enters a state of anergy. In this case, the T cell becomes tolerant to that antigen and is unable to divide or to secrete cytokines. This state of unresponsiveness to antigen is called anergy.
t cell lymphoma
cytotoxic t cell and helper t cell