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How does the pancreas prevent digesting itself with the peptidases it produces?
Wiki User
∙ 15y ago
Pancreatic enzymes aren't "activated" until they reach the small intestine. If they're activated just after they're produced, pancreatitis can result as the enzymes try to digest the pancreas.
Pancreatitis is very painful and often fatal. I have a cat with chronic pancreatitis who has to take steroids, probiotics, nutritional supplements, and antibiotics. Pancreatic enzymes aren't "activated" until they reach the small intestine. If they're activated just after they're produced, pancreatitis can result as the enzymes try to digest the pancreas.
Pancreatitis is very painful and often fatal. I have a cat with chronic pancreatitis who has to take steroids, probiotics, nutritional supplements, and antibiotics.
Wiki User
∙ 15y ago
Wiki User
∙ 11y agoenzymes are synthesized as inactive zymogens enzymes are segregated within membrane bound compartments pancreas contains intracellular trypsin inhibitor Þ inactivates any trace of trypsin mistakenly activated within pancreas the activating enzyme (enterokinase) is geographically separated from the pancreas http://d3jonline.tripod.com/21-Gastrointestinal/Disorders_of_the_Pancreas.htm
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