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263 miles taking this route:
- Follow I-64 WEST from Hampton to I-81 SOUTH to ROANOKE, via I-295 NORTH to bypass RICHMOND. (EXIT 200 off I-64 in Virginia to get onto I-295 NORTH ; EXIT 53A off I-295 to get back onto I-64 WEST).
- Take I-81 SOUTH to Roanoke. To get to DOWNTOWN, take I-581 SOUTH (EXIT 143 off I-81).
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