4 hours and 15 minutes
Buffalo, NY to Hilton Head Island, SC is about 900 road miles.
The shortest driving time is 4 hours and 15 minutes.
106 miles
Myrtle Beach. ...Hilton Head Island. ...Greenville. ...Camden. ...West Columbia. ...Anderson.
Charleston, SC. They also fly into Charlotte and Spartanburg, but those are pretty far away from Hilton Head.
It is 115.77 miles according to MapQuest.
It is 34.8 miles according to Google Maps.
650 miles
It is 150 miles according to Google Maps.
920 miles
253 miles