329 miles or 5 hours 49 min
about 55 miles taking NY-104A SOUTH to NY-104 WEST, and then NY-104 WEST to Rochester.
88 miles taking this route:Take NY-96 NORTH, from Ithaca, to I-90 THRUWAY (toll road) - WEST to BUFFALO. Follow signs.Take I-90 WEST, on the THURWAY, to I-490 WEST to ROCHESTER at EXIT 45.Take I-490 WEST to ROCHESTER.
80 miles taking this route:Take I-90 WEST, on the THRUWAY, to I-490 WEST to ROCHESTER off EXIT 45.Take I-490 WEST to ROCHESTER.
193 miles taking this route:Take NY-30 SOUTH from Amsterdam to I-90 New York State THRUWAY (toll road). Stay right on the exit ramp and go onto I-90 WEST.Take I-90 THRUWAY (toll) WEST to I-490 WEST to ROCHESTER at EXIT 45.Take I-490 WEST to Rochester.
about 350 miles
Rochester NY is approximately 115 miles northwest of Utica NY. The driving distance between the two cities is about 2 hours.
64 miles
about 370 miles
223 miles
Rochester NY is 726 miles from Charlotte North Carolina.
Rochester, NY is approximately 65 miles west of North Tonawanda, NY. The drive takes around 1.5 hours via I-90 W.
338 miles