575 miles taking this route:
It is 453.49 miles according to MapQuest.
It is 538 miles according to Google Maps.
The distance between Greenville SC and Tampa FL is about 567 road miles.
Spartanburg, SC
Sure
I believe it is Jacksonville.
318 miles
Gable, SC
It is 490.15 miles according to MapQuest.
It is 503.64 miles according to MapQuest.
Brunswick, GA
It will take about 10 hour to get there.