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Genesis 3:15, "And I will put enmity between you and the woman, and between your seed and her Seed; He shall bruise your head, and you shall bruise His heel." After God curses the physical serpent in verse 14 He then turns to the spiritual serpent, Satan. This "first gospel' is prophetic of the struggle and its outcome between "your seed" (Satan and unbelievers), who are called the Devils children (John 8:44, and her seed (Christ, a decendant of Eve, and those in Him. "He' is Christ who will one day defeat Satan. Satan could only bruise Christ heel, while Christ will bruise Satan's head(Destroy him with a fatal blow).

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