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For me it was determined by my hieght, weight, and how severe my acne was.

I am 6 feet tall and 155 pounds. I had acne on my cheeks, chin, nose, upper lip, and forehead. I had some on my neck and back of my neck. I got an occasional break out on my chest and upper back. My dosage was 30mg twice a day. I am in my third month and it has worked wonderfully!! Totally clear on cheeks, chin, nose, and upper lip. Still have some left on my forhead. The doctor said my pores will open up and allow for the bacteria sitting in my skin to come out. Once all the bacteria is out... no more break outs.

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Q: How is accutane dosage determined?
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