MHC class 1 receptors have different genes encoding it: HLA-A, HLA-B and HLA-C. Each gene come in two versions, mom and dad, so that is a total of 6 possibilities.
MHC is highly polygenic and polymorphic. HLA-A has 59 alleles, HLA-B has 111 alleles and HLA-C has 37 alleles. 59*111*37*6*2 = ~3 million combination. The odds that you will exactly match the same alleles as a donor is almost none. So they try to match several of the most important ones and even then it is very difficult. If your MHC's don't match well the organ receiver's adaptive immunity (specifically T cells) will recognize the transplanted organ as foreign and reject it.
The National Marrow Donation Program website gives details on how one can sign up as a potential donor. Around 1 in 500 program members go on to donate marrow.
Yellow marrow is bone marrow that is involved in fat storage as opposed to red marrow which is involved in the production of red blood cells.
Their are many things that are involved in donating bone marrow. Some things that are involved are money, blood and many more. The odds of a match are less than 25 %.
Information on bone marrow donation in Canada can be viewed at the website of the Canadian Blood Services. There is a comprehensive FAQ section which should answer many of your questions.
Red bone marrow is found in ribs , ends of long bones and is involved in RBC production .
Bones or Bone Marrow
In adults they are mostly produced in the bone marrow. There are situations where they can be produced elsewhere.
Red Bone Marrow and thymus gland
Platelets are involved in blood clotting. They are also called thrombocytes and come from the bone marrow.
Giving a person bone marrow allows them to make more red blood cell or white blood cells. Bone marrow is the ingredients to making these products. The circulatory uses the bone marrow from a donor.
You simply register with the national marrow donor program and then the cord will be taken after labor at the hospital where you give birth to your child.
Leighton Meester has supported:- ONE Campaign Charity (AIDS, Poverty)- DKMSCauses:- Blood, Marrow & Organ Donation- Cancer