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The third class of antiretroviral drugs developed against HIV were the protease inhibitors. These work far back in the life cycle of HIV, after host cell integration but before budding. These drugs affect the enzyme protease, which is used to cut up the HIV protein to be packaged into virions.
When the cell produces HIV proteins, the raw material is in a long connected string. The enzyme protease acts as a "scissor" to cut up the string into the protein for each virion. Protease inhibitors prevent protease from doing this. They resemble pieces of the protein string that protease usually cuts. This disrupts the cutting process, which prevents the chain from being cut into small pieces, which prevents HIV from making copies of itself.
What else can I help you with?
A drug that is used to treat AIDS by blocking the production of an enzyme?
The drug you are referring to is likely to be a protease inhibitor. Protease inhibitors work by blocking the enzyme necessary for the replication of the virus that causes AIDS, which helps prevent the virus from multiplying and spreading within the body. By inhibiting this enzyme, protease inhibitors are able to slow down the progression of the disease and improve the immune status of individuals with AIDS.
What is the generic name for Fortase?
The generic name for the brand name drug Fortase (protease inihibitor for HIV - AIDS) is saquinavir.
How does indinavir work?
Indinavir is a protease inhibitor used to treat HIV/AIDS. It works by blocking the protease enzyme, which HIV needs to replicate and spread in the body. This helps to reduce the viral load and slow down the progression of the disease.
What is the enzyme in pineapple called?
The enzyme found in pineapple is called bromelain. It is known for its ability to break down proteins and aids in digestion.
Which do you get first AIDS HIV or AIDS related diseases?
People contract HIV first. In time, they will develop AIDS-related diseases such as Kaposi's sarcoma or PCP (pneumocistis carinii pneumonia). Once they have AIDS-related diseases, they are typically diagnosed as having AIDS.
What is HIV protease inhibitor?
Protease inhibitors (PIs) are a class of medications used to treat or prevent infection by viruses, including HIV and Hepatitis C. PIs prevent viral replication by inhibiting the activity of HIV-1 protease, an enzyme used by the viruses to cleave nascent proteins for final assembly of new virons.
What does the medical abbreviation ARC mean?
AIDS Related Complex
When was AIDS identified as a disease?
AIDS was identified as a disease in 1982. For the history of AIDS, visit the Related Link.
What is the formula for protease?
Protease is an enzyme. It is essentially a protein. Protease is not a compound and therefore its formula cannot be given out. Protease are a class of enzymes involved in digesting proteins. The basic mode of action can be described as: Protein + Protease -----> Digested protein + protease Since enzymes do not react in a biochemical reaction (they are merely catalysis), protease appears on both sides of the reaction shown above
What is the total death by AIDS in Canada?
In 2009 there were 1000 AIDS related deaths in Canada.
What does protease producE?
Protease breaks down Protein into amino acids
Where does AIDS related Kaposi's sarcoma appear?
AIDS-related KS tumors generally appear on the upper body, including the head, neck, and back
