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How is the cause of an infectious disease established?

Updated: 8/21/2019
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10y ago

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That is a very good question. When you find a bacteria at the place where you do not find the same normally and then you get particular symptom and sign complex. Then you can say that this disease is caused by that particular organism. So when you are able to culture the bacteria from say blood or urine, where that is not found normally. Secondly after the infection of particular microorganism if you get the heightened antibody response you can say that particular organism is involved in that particular disease. Next you can have a statistical evidence to say that particular organism is responsible to cause the disease. So when you find streptococci in say 5 % of healthy persons and say 50 % of sore throat patients, you can say that this organism is associated with the pharyngitis.

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Q: How is the cause of an infectious disease established?
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