How long does 34 Mg of Concerta take to get out of your system for a clean ua?

Answer 1

it takes about 1-2 weeks

CONCERTA® uses osmotic pressure to deliver methylphenidate HCl at a controlled

rate. The system, which resembles a conventional tablet in appearance, comprises

an osmotically active trilayer core surrounded by a semipermeable membrane with

an immediate-release drug overcoat. The trilayer core is composed of two drug

layers containing the drug and excipients, and a push layer containing osmotically

active components. There is a precision-laser drilled orifice on the drug-layer end

of the tablet. In an aqueous environment, such as the gastrointestinal tract, the drug

overcoat dissolves within one hour, providing an initial dose of methylphenidate.

Water permeates through the membrane into the tablet core. As the osmotically

active polymer excipients expand, methylphenidate is released through the orifice.

The membrane controls the rate at which water enters the tablet core, which in

turn controls drug delivery. Furthermore, the drug release rate from the system

increases with time over a period of 6 to 7 hours due to the drug concentration

gradient incorporated into the two drug layers of CONCERTA®. The biologically inert

components of the tablet remain intact during gastrointestinal transit and are

eliminated in the stool as a tablet shell along with insoluble core components. It is

possible that CONCERTA® extended-release tablets may be visible on abdominal

x-rays under certain circumstances, especially when digital enhancing techniques

are utilized.

The mean half-life of CONCERTA® is about 3.6 hours.