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One 500mg dose of Cipro works for 12 hours. One 500mg tablet has a four hour half life - meaning it takes approximately eight hours for one 500mg dose to be eliminated from your bloodstream; that is, after the initial 12 hours that the drug is working in your system. So, if you took one 500mg tablet at noon, by approximately 8AM the next morning, it should be eliminated from the bloodstream, considering you do not take a second dose before that time. Otherwise, you have to account for each dosage you take.

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15y ago
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13y ago

Cipro is no longer recommended for treatment of gonorrhea due to increasing antibiotic resistance. Please contact your health care provider and ask them to prescribe a medication consistent with current treatment recommendations.

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12y ago

how long does cipro stay in your system after use

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14y ago

How long does ciprofloxacin hcl keep working after the last pill?

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11y ago

24 hours

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11y ago

24 hours

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11y ago

1 day

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Q: How long does it take Cipro to leave your system?
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