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It usually takes about 1.5 to 2hrs for me to feel the slight effect of my Vyvanse. It works MUCH better if I take it with a small meal !!! It usually takes about 1.5 to 2hrs for me to feel the slight effect of my Vyvanse. It works MUCH better if I take it with a small meal !!!

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15y ago
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14y ago

Depends how much you took, if you took 70mg probably 12 hours or so but if you took a real high dose like 140mg probably 18 hours maybe a little more. A little more kick to it than 5 hour energy.

Lisdexamfetamine is a prodrug of dextroamphetamine. After oral administration,

lisdexamfetamine is rapidly absorbed from the gastrointestinal tract and

converted to dextroamphetamine, which is responsible for the drug's activity.

In 18 pediatric patients (aged 6 to 12) with ADHD, the Tmax of dextroamphetamine

was approximately 3.5 hours following single-dose oral administration of lisdexamfetamine

dimesylate either 30 mg, 50 mg, or 70 mg after an 8-hour overnight fast. The

Tmax of lisdexamfetamine was approximately 1 hour. Linear pharmacokinetics of dextroamphetamine

after single-dose oral administration of lisdexamfetamine dimesylate

was established over the dose range of 30 mg to 70 mg in children aged 6 to 12 years.

There is no unexpected accumulation of dextroamphetamine AUC at steady state in

healthy adults and no accumulation of lisdexamfetamine after once-daily dosing for

7 consecutive days.

Food does not affect the observed AUC and Cmax of dextroamphetamine in healthy

adults after single-dose oral administration of 70 mg of Vyvanse capsules but

prolongs Tmax by approximately 1 hour (from 3.8 hrs at fasted state to 4.7 hrs

after a high fat meal). After an 8-hour fast, the AUCs for dextroamphetamine

following oral administration of lisdexamfetamine dimesylate in solution and as

intact capsules were equivalent.

Weight/Dose normalized AUC and

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12y ago

You should start feeling it kicking in around 30 mins and full effects in 45 mins to an hour (give or take a few depending on how empty your stomach is and how quickly your body metabolizes medicine) Hope this helped :)

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Q: How long does it take for full effects of Vyvanse to start showing?
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