The driving distance between Buffalo, NY and New York, NY is approximately 375 miles. The driving time would be approximately 6 hours 30 minutes if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work, border crossings and rush hour traffic in urban areas.)
Drive: about 2 hours
Assuming you meant Buffalo, NY to Manchester, NY. They are about 90 miles apart on the I-90E - 1.5 hours.
24 hours
The distance between Buffalo, NY to Hilton Head, SC is about 912 miles which is about 15 hours and 8 minutes drive.
15 hours 38 minutes
1 hour and 55 minutes.
The trip from Oakville, Ontario to Buffalo, NY takes about 2 hours; with a distance of 76.38 miles according to MapQuest.
The distance between Buffalo, NY, and Raleigh, NC, is 669 miles and will take approximately 11 Hours 33 Minutes of driving time.
Go west on i-80 Will take 1day 16 hours 2,483miles
37.5 kilometers/23.3 miles 27 minutes
Google Maps estimates the driving time as 20.25 hours.
I takes about 1 hour and 54 minutes to drive from Buffalo,NY to Toronto,Ontario,Canada.