The driving distance between Cincinnati, OH and St. Louis, MO is approximately 365 miles. The driving time would be approximately 6 hours if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work, border crossings and rush hour traffic in urban areas.)
5 hours and 16 minutes
5 to 5 and 1/2 hours
www.mapquest.com
Google Maps estimates the driving time as 5 hours and 58 minutes.
How long does it take to drive from St. Louis Mo to Lake Florida
about 2 days
How long does it take to drive from St. Louis MO. To San Diego VS.
4-5 hrs
About 3.5 hours.
too long grab a flight
Check Mapquest.com
It is 1,192.56 miles according to MapQuest.