The driving distance between Kansas City, MO and Jacksonville, FL is approximately 1125 miles. The driving time would be approximately 19 hours if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work, border crossings and rush hour traffic in urban areas.)
MapQuest gives the estimated driving time as 14 hours and six minutes.
About 4 hrs
It is 1,465.66 miles and a 22 hour and 58 minute drive according t MapQuest.
That would depend on where in Florida and where in Missouri you are.
1 EverBank Field Drive Jacksonville, Florida 32202
Mapquest
About 3.25 hours.
The fastest route to drive from Orlando Florida to Jacksonville Florida is on a US Interstate highway. In this case that highway is Rt. 95.
Chattanooga, Tennessee is midway along the drive from Kansas City, Missouri to Fort Myers, Florida.
19 hours.
Arrowhead Stadium, home of the Kansas City Chiefs, is located at One Arrowhead Drive, Kansas City, Missouri, Jackson County
Orlando, Florida to Jacksonville, Florida is 2 h 7 min (141.2 mi) via I-4 E and I-95 N