5 hours
About 3.5 hours, depending on traffic and weather.
It depends on where you are going in Louisville. From Frankfort to the east side of Louisville the drive is 35-40 minutes.
According to MapQuest and depending on where you start out in Louisville and go to in Birmingham, it will take at least 5 hours and 35 minutes to drive.
Almost 14 hours.
According to mapquest.com, it will take approx. 16 1/2 hours to drive the 1083.76 miles from Miami Florida to Louisville Kentucky.
34 hours
Chigago IL to Louisville, KY, USA 297 mi - about 4 hours 47 mins
It is 106.67 miles according to MapQuest.
three and a half hours
8 and 1/2 hours
It would take about 31.26 Hrs. a distance of 2145.59 miles. And it will be hot when you get there.
Google Maps estimates the driving time as 5 hours and 8 minutes.