The driving distance between Des Moines, IA and Jacksonville, FL is approximately 1210 miles. The driving time would be approximately 21 hours 15 minutes if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work, border crossings and rush hour traffic in urban areas.)
24 hours
Just about two hours.
About 6 hours if you drive the speed limit...
The drive from Orlando to Jacksonville via I-4 and I-95 is approximately 2.5 hours.
About three hours.
around 5 hours
The drive would take about 8 hours.
a long time
It will take about 15 hours and 1 minute to drive from Allentown PA to Jacksonville Florida. Cited by: Google Maps
The drive would take about 13 to 14 hours.
It will take you approximately 4 hours to drive from Fort Lauderdale, FL to Jacksonville, FL. It is 325 miles between the two cities.
13 hours