Both are very large states. Travel time will depend on WHERE you start from in PA, and WHERE you end in NC. Please repost with specific start and stop points (cities).
It takes about 8 hours 3 minutes to drive from Harrisburg, Pennsylvania to Charlotte, North Carolina if you travel via I-81 S and I-77 S.
6 hours
Alexandria Virgina to Jacksonville North Carolina the drive will be 5 hours and 23 mintues
the drive is 580.57 miles from North Carolina to Alabama, or 9 hours and 32 minutes
It takes about 12 ½ hours to get from Miami, Florida to Raleigh, North Carolina, which is the capital of North Carolina and close to the middle of the state.
It is 460 miles (8 hours 49 minutes) from Wilkes Barre, Pennsylvania to Outer Banks, North Carolina.
16 Hours
It is 443 miles and an estimated driving time of 8 hours and 9 minutes according to Google Maps.
it takes 11 hours and 26v minutes to drive from Atlantic North Carolina to New York
The shortest time is 16 hours, and you go through Pennsylvania, New Jersey, Delaware, Maryland, Virginia, North Carolina, and South Carolina.
about 6 and 1/2 hours
6 hours to get to the state line.