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It takes 6 to 8 weeks of drug therapy to see improvement. About 1/3 of patients become weaker temporarily after starting prednisone, usually in the first 7 to 10 days, but this weakness is temporary.

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Q: How long is life expectancy with myasthenia gravis?
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How long does improvement last for treatment of myasthenia gravis from plasma exchange?

Improvement lasts for weeks or months and then the effect is lost unless the exchange is followed by thymectomy or immunosuppressive therapy.


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Mysthenia Gravis (MG) is a disease mediated by antibodies which attack the receptors on muscles and decreases their ability to contract (to be stimulated to contract actually). The thymus gland is an organ involved with the maturation of T-lymphocytes which are involved in the production of antibodies. An association with tumors of the thymus gland and the onset of myasthenia gravis was noted and removal of thymomas has been shown to be effective in treating MG. Extending from this knowledge surgeons have removed normal appearing thymus glands in patients with MG and this has been proven in some large studies to be effective in decreasing the severity of myathenia gravis over the long term.


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