It requires an estimated 3 hours of driving time and is 179.55 miles according to MapQuest.
179 miles
A drive of 116 miles which is about 2 hours 18 minutes.
The distance between Buffalo, NY to Hilton Head, SC is about 912 miles which is about 15 hours and 8 minutes drive.
10 hours
A long drive, just google it.
Six hours.
it is approximately 2 hr"s and 45 minnutes
The shortest time is 12 hours.
About 4 hours on US-17
4 hours and 15 minutes
7 hours and 16 minutes
It is 808 miles according to Google Maps.