It is 776 miles according to Google Maps.
The distance to cover is about 1300 miles, which boils down to roughly 21 hours of real driving. (This is not counting stops.)
Cincinnati OH is already in Ohio.
Google Maps estimates the driviing time as 14 hours and 52 minutes.
Google estimates the driving time as 12 hours and 24 minutes.
Google Maps estimates the driving time as 12 hours and 59 minutes.
Google Maps estimates the driving time as 17 hours and 52 minutes.
Google Maps estimates the driving time as 15 hours and 59 minutes.
Google Maps estimates the drivng time as 15 hours and 38 minutes.
The Ohio River is 981 miles long. The distance between Pittsburgh (which is on the Ohio) and Key West is 1332 miles.
Google Maps estimates the driving time as 15 hours and 45 minutes.
Google Maps estimates the driving time as 15 hours and 44 minutes. The distance is 954 miles.