Google Maps says that it is 563km from Dusseldorf to Berlin and should take 5 hours 15 minutes.
berlin, frankfurt, dusseldorf
around 600 Kms
Straight line distance in an aircraft is around 450km!
2h46m33s
Take the A2 / 563 km - about 5 hours 15 mins.
It would take less than an hour. It takes an hour to fly from Amsterdam to Berlin which is much further away that Dusseldorf which is just at our border.
625 km or 388 miles. If you drive with a car, you could be in around 6 hours in Berlin.
7 hours
8 hours
8 and 1/2 hours
10 and 1/2 hours