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never in most cases, unless you assume the antibiotic as a placebo. I believe sinus infections aren't usually bacterial, in which case antibiotics are useless, and not only usless--by taking them you are raising your tolerance to them and speading MRSA, raising other people's tolerance, and assisting in causing worlwide antibiotic resistance, which s a horrible thing--HOWEVER, once the infection has developed it can become bacterial, which has happened to me, and i find that you would start feeling better within a few days to a week. but also beware, these infections tend to return!

In most clinical studies, patients with sinusitis get better in 7 to 10 days, whether or not they take antibiotics.

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Q: How long will it take for antibiotics to work before you feel relief of an earache and jaw pain?
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