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The literature says to allow as long as 6 weeks.

However when I was placed on depakote for Bipolar disorder, I was feeling that something was different within about 3 days of the first dose (although I was not sure what was different at that time).

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8y ago
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11y ago

It's been longer then a week and the hot flashes are still present.

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8y ago

Some side effects may appear instantly (e.g. stomach upset) but others may take months or years.

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Q: How long will it take to see effects of depakote?
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