"About 18 hours" was the answer here. Having done this trip many times, I'll expand that a little. If you pick your time of travel with care, use the toll roads, and stop only for fuel, then 15 hours is achievable. This is what I prefer to do: depart Calais 0200, arrive Barcelona 1700. However, this is not exactly a relaxing journey and it can be a hard drive.
If you prefer something more relaxing then 18 hours is probably too little to allow. I believe that coach services allow double this.
about 5 and a half hours
15 Hours non stop
How long does it take to drive from Trier in germany to Calais?
There is 743 miles between Calais, France and Genoa, Italy. The drive would take about 11 hours to complete by car. Flying would take about an hour and a half.
About 4h45
342miles
three month
19 hours
36 hours
The distance (according to Google Earth) is 1,353km and would take about 13 hours 41 mins to drive.
It takes about an hour and a half to drive the 73 miles from Palamos to Barcelona.
the distance from Calais to Biarritz is 1070 km. This is a driving time of nearly ten hours.