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how many chromosomes are in sickle cell

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Bennett Bode

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2y ago

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Is there to many or too less chromosomes in sickle cell anemia?

Neither. People with sickle cell anemia have the same number of chromosomes and even the same number of genes as those who don't have the disease. The difference is a *change* in one of the genes. Actually, it is (usually) caused by a one letter difference in the hemoglobin gene which makes the hemoglobin produced more 'sticky' on a molecular level.


When was sickle cell anemia discovered?

Sickle cell anemia was first described in the medical literature in 1910 by Dr. James B. Herrick, who identified the unique sickle-shaped red blood cells in a patient of African descent. The genetic basis of the disease was later elucidated by Dr. Linus Pauling in the 1940s.


Why sickle cell anemia resistance malaria?

Sickle cell anemia comes as the result of having two sickle cell chromosomes. One sickle cell chromosome makes people resistant to malaria. Unfortunately when people have two sickle cell chromosomes they can get sickle cell anemia. That makes it difficult for their blood to carry oxygen and under certain conditions makes their blood clump. The disease can be deadly. Drugs can help. It probably makes that person resistant to malaria. The sickle cell trait evolved in various places around the world where malaria is common such as Africa and Greece.


How many amino acids need to be incorrect to prevent protein from working properly in sickle cell anemia?

Just one incorrect amino acid prevents protein from functioning properly in sickle cell anemia.


What are people with sickle cell resistant to?

Sickle cell anemia provides resistance to malaria - it is ideal for many people in Africa that live in mosquito rampant areas.


How many people in the US have sickle cell anemia?

About 70,000 Americans have it. About 2 million carry the gene for it.


Does sickle cell anemia cause decayed teeth?

I have sickle cell and scapular necrosis occurred because the none in my joints became soft from the many crises I had. My teeth also was affected and severe decaying occurred. My dentist said it was because of the necrosis and sickle cell.


What is genetics disorders?

A genetic disorder is something you inherit from birth , it could complicate the person's whole life. ex.(sickle cell anemia,SCIDS,Turner sydrome,ans many many others.)


What is the common name for sickle cell anemia?

It is a genetic disorder. However... It is also a protection against malaria. For example, if a person were born in an area where malaria is present, he or she would likely die from the disease, unless he or she inherited 1 sickle cell gene. Malaria viruses reproduce in the red blood cells. The parent virus invades a cell, and uses the cell as a host to grow more viruses. With 1 sickle cell gene, malaria viruses that invade a red cell are quickly destroyed, since the red cell collapses, preventing the virus from reproducing. But with 2 sickle cell genes, red cells collapse too easily; just a bruise can cause someone to become anemic when too many red cells collapse. In the real world, people with no sickle cell genes died from malaria. People with 1 sickle cell gene survived. People with 2 sickle cell genes died from sickle cell anemia. It was natures way of assuring that at least half of the population survive, but it is certainly a difficult thing to live with today, now that we can more easily treat malaria.


Is sickle cell anemia congenital?

Sickle-cell is inherited from parents just as physical traits. People with the disease are SS type and show the anemia. Others can carry the trait (Ss). They are able to fight off malaria. Since this type (Ss) is important in areas with many malaria cases, this is protective.


Is sickle cell anemia a disease from mutation?

Yes, but the mutation happened many many thousands of years ago. It has been passed on through all these generations because the same gene that causes sickle cell anemia in a person that inherits two copies of the gene also causes resistance to the malaria parasite in a person that inherits only one copy of the gene. In areas of the world where malaria is a common disease, the resistance to it is a stronger selective advantage than sickle cell anemia is a selective disadvantage; so the gene becomes very common in those populations.


What are two types of blood diseases?

Diseases that affect your blood include:AnemiaAnemia, AplasticAnemia, FanconiAnemia, HemolyticAnemia, Iron-DeficiencyAnemia, PerniciousAnemia, Sickle CellAntiphospholipid Antibody SyndromeDeep Vein Thrombosis (DVT, Thrombophlebitis)Disseminated Intravascular Coagulation (DIC)Excessive Blood ClottingHemochromatosisHemophiliaImmune Thrombocytopenic Purpura (ITP)LeukemiaLymphocytopeniaPolycythemia VeraPulmonary EmbolismRh IncompatibilityThalassemiasThrombocytopeniaThrombocythemia and ThrombocytosisThrombophlebitis (Deep Vein Thrombosis, DVT)Thrombotic Thrombocytopenic Purpura (TTP)Von Willebrand Disease