How many miles between Hattiesburg and Detroit MI?

Answer 1

1,000 miles taking this route:

1. Take I-59 NORTH from Hattiesburg up to I-24 EAST to CHATTANOOGA in Georgia (I-24 briefly dips into Georgia before returning back into Tennessee).
2. Take I-24 EAST to I-75 NORTH to KNOXVILLE at EXIT 185B.
3. take I-75 NORTH to Detroit.

The half-way point is Clinton, Tennessee (EXIT 122 off I-75, 20 miles north of Knoxville). I would highly recommend that you stay here overnight. There are plenty of Hotels, gas, food, etc.