How many miles is it from Fort Myers FLto Daniel Island SC?

Answer 1

605 miles taking this route:

1. Take I-75 NORTH, from Ft. Myers, all the way up to I-10 EAST to JACKSONVILLE at EXIT 435 in Lake City.
2. Take I-10 EAST to I-95 NORTH to SAVANNAH, via I-295 NORTH to bypass JACKSONVILLE (EXIT 356 off I-10 to get onto I-295, follow signs to I-295 NORTH to SAVANNAH ; EXIT 35B off I-295 to get onto I-95 NORTH to SAVANNAH.
3. Take I-95 NORTH to U.S. 17 to CHARLESTON at EXIT 33 in South Carolina.
4. Take U.S. 17 NORTH to I-526 EAST to NORTH CHARLESTON.
5. Take I-526, around Charleston, to Daniel Island, SC.