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The amount of hydrocodone needed to induce euphoria is highly dependent on tolerance: opioid naive individuals may very well need only one or two 5mg pills, whereas a very opioid-tolerant person may need hundreds of milligrams. This can also vary to a lesser extent based on other factors of individual physiology.

However, abusing painkillers can be highly dangerous and thus strongly discouraged. Risks include addiction, overdose (especially in new users who take too much), and liver damage from the acetaminophen (500mg) in the pills. The maximum recommended daily dose of acetaminophen is 4000mg, with toxicity manifesting around double that. While this may not be significant for a person with low tolerance (the hydrocodone itself being the major overdose concern in this case) one with a high tolerance may easily exceed the toxic dose of acetaminophen and risk severe health complications.

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13y ago

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