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The heme "assembly line" is an eight-step process, requiring eight different and properly functioning enzymes.
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What is significant about heme biosynthesis?
Heme biosynthesis is significant because heme is a crucial molecule involved in many important biological processes, such as oxygen transport, energy production, and drug metabolism. Defects in heme biosynthesis can lead to various disorders, including porphyrias, which are characterized by abnormal heme production and can result in symptoms such as skin sensitivity to sunlight, abdominal pain, and neurological symptoms. Understanding heme biosynthesis can help in the diagnosis and treatment of these disorders.
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