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no its not, ive built up a large tolerance to anti-histamines. Although it may make the average person extremely sleepy, and it isnt recommended to take that much of any anti-histamine. All it really is is Benadryl, ive taken upwards 200mg of zzzquil (which is the same thing). You will be fine.

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11y ago
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10y ago

It's tough to "overdose" on benadryl, but yes, 250mg is about 5 times the normal dose. Each beladryl caplet is 25mg, and that's the equivalent of 10 pills. It probably won't hurt you, but you'll be groggy and sleepy for quite a while.

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Q: How much diphenhydramine will cause a fatal overdose?
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