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It is impossible to answer this question without a significant amount of additional information. For example -- how much alcohol? One beer or fifty?

The important bit of information here is that any amount of oxycodone, mixed with any amount of alcohol, is *potentially* fatal.

The patients developed tolerance for the two drugs will have a large effect on the lethality of a given dose. Regardless, this combination is always to be avoided.

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Q: How much oxycodone would kill you when mixed with alcohol?
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