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The smallpox vaccine was the first successful vaccine to be developed.

Edward Jenner observed that milkmaids who caught the cowpox virus did not catch smallpox.

He started testing by infecting people with actual Cowpox and after successfully finding this to be effective, "mass infecting" people with Cowpox took place.

This reduced mortality by Smallpox drastically.

Cowpox and Smallpox are closely related but Cowpox only gives the disease in a very mild form in humans. This most likely because it has developed towards cows and not humans.

Diseases do not cross the species barrier easily.

As a result of the similarities between the two, human bodies start building up an immune respons against both diseases even if only Cowpox is present.

Read more at related link below.

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Brennan Jacobs

Lvl 10
2y ago

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