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You should not take two different pain medications together. Separate ibuprofen and acetaminophen by at least 3 hours. Acetaminophen can cause damage to the liver in high dosages. Ibuprofen is hard on the stomach, and can cause ulcers or bleeding at high doses. The best way to take these medicines is by using the "Three Hour Switch" that every parent learns - take one, wait 3 hours then take the other one, wait 3 more hours and take the first one again, etc.

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15y ago

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