The Circulatory, Lyphatic, Integumentary, Muscular, and Nervous Systems.
the muscle, tissue, and possibly the bone
mammary glands and hair.
guts is a widely used term refering to the internal organs of an animal... sharks do have organs just like us humans. Very different organs but organs, so the answer would be yes.
muscles..
organelles>cells>tissues>organs>organsystem
If the cardiovascular system doesn't work, then obviously organs would be affected. The first organ affected will be the lungs.
the circulatory system
The respiritory system would be impaired (depending on the stage of the cancer). As the word "lung" & "respiritory" suggests, the person may have trouble breathing, and may be short of breath.
The relationship between cells,organs, and systems would be many cells make up tissue, many tissues make up an organ, many organs make up an organ system, and organ systems make up and organism.
Directly, your skeletal system is affected since the Anterior Cruciate Ligament (ACL), being a ligament, connects the Femur to the Tibia. Indirectly, the affected systems would be: muscular, nervous, and integumentary systems.
The fungi is related to the mushroom.
your judgment would be affected first.