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I assume you are talking about a long-acting oxycodone tablet such as Oxycontin. Short-acting forms of the drug are not prescribed in that kind of dose.

And it is highly unlikely you would pass said urine screen. Long-acting oxycodone stays in therapeutic concentrations in blood plasma for a full 12 hours AT LEAST. Depending on your personal metabolic rate for opiates you might not feel it working that long, but it is in there. That means your body should be excreting opiate metabolites for the following 72 hours after one dose of a drug like oxycontin.

If you have a drug screen coming up and you really want to pass it: don't take the oxy.

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Q: If you took 1 40mg oxycodone on Sunday will you pass a urine test on Tuesday?
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