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well, that's what i understand and am not an expert
there is nuclear cytoplasmic dissociation in which the immaturity is for the nucleus only but the cytoplasmic organelle are mature
folate is needed in production of thymine (purely DNA) but to get RNA you dont need it uracil)
so you will have mature cytoplasm in which HG is normally formed (not arrested)
MCHC is normal but MCH is elevated coz MCH is dividing the HG by RBC count which will give you the HG per cell,, which is higher simply because you have a larger space (big cell) but MCHC is not elevated (not hyperchromic)
hope it helped
Mansour
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∙ 14y ago
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What does it mean to have high MCH on bloodwork?
MCH in blood work refers to Mean Corpuscular Hemoglobin. This is the concentration of hemoglobin in blood cells. High MCH can mean macrocytic anemia, which results from a deficiency in vitamin B12 or folic acid.
What is a normal MCH range?
28-32 pg
What does a high MCH mean?
normal range of mch is 27-32pg. mch means corpuscular hemoglobin. i think it can be high in polycythemia.
Is a MCH count of 31.1 within the normal range?
as far as i can see between 25.0- 34.0 is normal at least that is what i understand.
What does it mean when your MCH is low?
There are several things that might cause a low MCH test result. Some of these things include blood loss, low iron, or microcytic anemia.
What does it mean when the MCH is high in your cbc count?
MCH = Mean Corpuscular Hemoglobin. It is a measure of the amount of hemoglobin in your red blood cells. The ref. range for adults is between 28-32. MCH [similar to the MCV] is elevated in: hereditary anemia(s), megaloblastic anemias (pernicious, folic acid deficiency, B12 deficiency), reticulocytosis, artifact (aplasia, myelofibrosis, hyperglycemia, cold agglutinins), liver disease, hypothyroidism, Drugs (anti-convulsants), zidovidune treatment (AIDS).
I have a MCH of 32.2, Pg, a given Range by the clinic of 27.0 - 31.0: Is this too high and cause for attention ?
“I have a MCH of 32.2, Pg, a given Range by the clinic of 27.0 - 31.0: Is this too high and cause for attention? ”
What does it mean if your mcv and mch are low?
On a hematology lab report, MCV usually is meant to indicate the mean cellular volume of red blood cells. Normal values for MCV are between 80-100 fL for most adults. A low MCV could indicate many different things. The most common or prevalent being anemia. There are many different kinds of anemia, and there is no way to diagnose anemia without other laboratory testing. It could be iron deficiency anemia or it could be a range of genetic variations in hemoglobin composition, known collectively as thalassemias.
What does a low Mean Corpuscular Hemoglobin level mean?
When Mean Corpuscular Hemoglobin level is low or commonly known as MCH, this means a person has iron-deficiency anemia. This type of anemia can be caused by insufficient iron in the diet or blood loss.
What does a high MPV mean?
High MPV means that you have more than normal blood platelets. Your doctor will probably run more tests to check for things like leukemia.
What does a high MCH Lab test reveal?
MCH.
What does a high lymphocyte and a high MCH count mean?
Mean Corpuscular Hemoglobin (MCH) Normal Range: 26-34 pg (picograms/cell)The mean corpuscular hemoglobin, or "mean cell hemoglobin" (MCH), is the average mass of hemoglobin per red blood cell in a sample of blood. It is reported as part of a standard complete blood count.It is diminished inmicrocytic anemias and increasedin macrocytic anemias.It is calculated by dividing the total mass of hemoglobin by the number of red blood cells in a volume of blood. MCH=Hgb/RBC reference: http://en.wikipedia.org/wiki/Mean_corpuscular_hemoglobin---- Macrocytic Anemia* Types of macrocytic anemias ** 1.1 Megaloblastic anemias (DNA replication disorders) ** 1.2 Red cell membrane disorders producing codocytes ** 1.3 Alcohol ** 1.4 Association with rapid red cell turnover and reticulocytosis * Especially common causes of macrocytic anemias are the so-called megaloblastic anemias, in which cells are larger because they cannot produce DNA quickly enough to divide at the right time as they grow, and thus grow too large before division. Causes for the DNA synthetic problem range from lack of certain vitamins needed to produce DNA (notablyfolate and B12), to poisons or inhibitors of DNA replication, such as some kinds of antiviral drugs and chemotherapeutic agents.The remainder of the article can be seen on the following pagereference: http://en.wikipedia.org/wiki/Macrocytic_anemia* Macrocytosis, sometimes without associated anemia, is often evident in persons with chronic alcoholism. Although the macrocytosis of alcoholism may be secondary to poor nutrition with a resulting folate or vitamin B-12 deficiency, it is more often due to a direct toxicity of the alcohol on the marrow. The macrocytosis of alcoholism usually reverses only after months of abstinence from alcohol. The remainder of the article can be seen on the following pagereference: http://www.emedicine.com/med/topic1381.htm
