Want this question answered?
The 1953 Nature paper by James Watson and Francis Crick stated that each base pair (purine-pyrimidine pair, A-T and C-G) was held together by two hydrogen bonds.It is now established that, while this is true for adenine-thymine (A-T), the cytosine-guanine (C-G) pairing involves three hydrogen bonds.For a reproduction of the original paper, see:http://www.nature.com/nature/dna50/archive.html
- Bond angles - Bond lengths - The location of hydrogen atoms - Chargaff's pairs (although he didn't recognize them at the time)
He didn't. DNA was already known before Crick, Watson, Wilkins and Franklin discovered its chemical structure in the early 50s. Crick and Watson published in "Nature" in April of 1953.
The rule A-T; C-G is a complementary base pair, and is semi-conservative replication. The Hydrogen bonds will always pair in these exact pairs.
There is debate and controversy about who actually discovered the double helix. The two who made the report of the discovery was James Watson and Francis Crick. But their work was believed to be only possible through the discoveries by others, such as Raymond Gosling, Alexander Strokes and Herbert Wilson.
watson-base pairing
well the dna molecule model was compared to Franklins
well the dna molecule model was compared to Franklins
A is always with T and C is always with G
James Watson and Francis Crick are credited with the base pairing rules and DNA structure in general. Erwin Chargaff is credited with the rules of base pairs in that the number of pyrimidines is equal to the number of purines.
The 1953 Nature paper by James Watson and Francis Crick stated that each base pair (purine-pyrimidine pair, A-T and C-G) was held together by two hydrogen bonds.It is now established that, while this is true for adenine-thymine (A-T), the cytosine-guanine (C-G) pairing involves three hydrogen bonds.For a reproduction of the original paper, see:http://www.nature.com/nature/dna50/archive.html
The 1953 Nature paper by James Watson and Francis Crick stated that each base pair (purine-pyrimidine pair, A-T and C-G) was held together by two hydrogen bonds.It is now established that, while this is true for adenine-thymine (A-T), the cytosine-guanine (C-G) pairing involves three hydrogen bonds.For a reproduction of the original paper, see:http://www.nature.com/nature/dna50/archive.html
He is Paul's younger Brother. Stephen is now deceased as of 2012.
if you mean the double helix in DNA.....In 1953, based on X-ray diffraction images[123] taken by Rosalind Franklin and the information that the bases were paired, James D. Watson and Francis Crick suggested[123] what is now accepted as the first accurate model of DNA structure in the journal Nature.[5] Experimental evidence for Watson and Crick's model were published in a series of five articles in the same issue of Nature.[124] Of these, Franklin and Raymond Gosling's paper was the first publication of X-ray diffraction data that supported the Watson and Crick model,[125][126] this issue also contained an article on DNA structure by Maurice Wilkins and his colleagues.[127] In 1962, after Franklin's death, Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine.[128] However, debate continues on who should receive credit for the discovery, as the Watson and Crick article in Nature was based on Franklin's data without either acknowledgment or her knowledge.[129]
- Bond angles - Bond lengths - The location of hydrogen atoms - Chargaff's pairs (although he didn't recognize them at the time)
Uracil in Watson-Crick base-pairing though non-standard pairs exist.
andrew.lw@bigpond.com