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In the absence of any regulatory mechanisms what effect do you think an increase in blood pressure would have on glomerular filtration rate?
Wiki User
∙ 13y ago
Generally speaking, it would increase.
However, it depends on the reason for the hypertension. For instance, if there is an obstruction or constriction of the renal artery (stenosis, malignancy, etc...) the physiologic affect would to increase the body's BP. This is due to the fact that the obstruction is decreasing hydrostatic pressure to the glomerulus, and transiently decreasing GFR. The body compensates by increasing BP to increase GFR. Patients that present with a renal artery stenosis could in fact be hypertensive with a decreased GFR.
Wiki User
∙ 13y ago
Wiki User
∙ 13y agoThe rate of GFR will increase if the blood pressure increases, and will decrease if the plasma oncotic pressure increases.
GFR=certain coefficient*arteriolar hydrotstatic pressure - (arteriolar oncotic pressure + glomerular hydrostatic pressure).
Now, to put it very simply the arteriolar hydrostatic pressure is what the mean blood pressure in the afferent arteriole, so if it increases the GFR is bound to increase.
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What is the effect of constricted arterioles in the glomerular filtration rate?
Decreasing the diameter of the efferent arteriole would increase the hydrostatic pressure inside the glomerulus and effectively increase the glomerular filtration rate. If you increase the diameter of the afferent arteriole you would achieve the same effect.
How do you increase your GFR?
To increase your glomerular filtration rate, blood flow needs to be increased to the kidneys and the impaired kidneys function restored. The glomerular filtration rate, of GFR, measures how much blood passes through the glomeruli into the kidneys each minute.
What regulatory mechanisms would occur in response to a sudden increase in blood pressure?
Sudden vasodilation
Describe the effect of increasing the beaker pressure on glomerular pressure?
An increase in beaker pressure causes an increase in glomerular pressure.
How can sodium losses in the urine during water-induced diuresis be replaced?
-Increase in alderstone secretion -Decrease in glomerular filtration rate (GFR) -Increase in ADH (antidiuretic hormone) secretion -Decrease in secretion of atrial natriuretic peptide
What is regulatory mechanisms?
Regulatory mechanisms are those that are systems of contol in keeping the internal environment relatively stable and maintained within narrow limits, despite external environment change. Mechanisms like this include the Negative Feedback system, in which change in a variable is detected (e.g. increase) and action occurs to produce a change in the opposite direction (e.g. decrease).
How could adjust the afferent or efferent radius to compensate for the effect of reduced blood pressure on glomerular filtration rate?
increase afferent radius or decrease efferent radius depending on the degree of change in blood pressure
How do you increase filtration rate under constant pressure?
increase the area of filtration
Why does blood get filtered by the kidneys?
Blood pressure promotes filtration of blood in the kidneys by, generally, being greater in pressure than blood colloid osmotic pressure and glomerular capsule pressure which produces a net filtration pressure of about 10 mm Hg. Net filtration pressure forces a large volume of fluid into the capsular space. When blood pressure increase or decreases slightly, changes in the diameters of the afferent and efferent arterioles can actually keep net filtration pressure steady to maintain normal glomerular filtration. Constriction of the afferent arteriole decreases blood flow into the glomerulus, which decreases net filtration pressure. Constriction of the efferent arteriole slows outflow of blood and increases net filtration pressure.
How could increased glomerular filtration lead to increased urine output?
This means that there is more volume being excreted out of the body, therefore hydrophillic drugs usually clear rapidly from the body .
What would happen to the filtration rate if you apply pressure to the filtration system?
It would increase
What would happen to the filtration rate if you were to apply pressure to the filtration system?
It would increase.
