No. Huntington's Disease is a pathological process affecting subcortical structures, not the cerebellar cortex. It does cause generalized atrophy of the cerebral cortex, over time, however. It is a genetic disorder, autosomal dominant in its transmission process, and occurring on chromosome number 4.
There are dozens of diseases caused by a genetic defect. They are known as genetic diseases. Sickle Cell anemia, Hemophilia, Tay-Sachs, Huntingtons Disease- and many others are genetic diseases.
Huntington's disease is the result of a genetic defect on chromosome 4. This defect causes an excessive repetition of a section of the DNA on this chromosome. A unique characteristic of this disease is that as this gene gets passed down from generation to generation, the number of repeats of this DNA section increases. The more repeats that occur, the greater the chances of the carrier to develop symptoms of the disease at a younger age.
recessive defect meaning that both copies of the chromosome must have the defect before it can be expressed. Females who have one X chromosome without the defect do not get this disease. Males, since they only have one X chromosome, get the disease
A Congenital Heart Defect
Nephritis, a congenital kidney defect.
PKU
In Pompe's disease, the defect lies in the lysosomal enzyme alpha-glucosidase, which leads to the accumulation of glycogen in lysosomes. In Tay-Sachs disease, the defect is in the enzyme hexosaminidase A, which leads to the accumulation of GM2 gangliosides in lysosomes.
A defect in the cell-mediated immune system response was identified with regard to Hepatitis B (with many articles written about this in 2008-2009). HIV-AIDS is another disease with a defect in cell-mediated immune response, as well. There are other immunodeficiency diseases involving this kind of defect, too. immunological deficiency syndroms
Gaucher disease is caused by a genetic defect in an enzyme called glucocerebroside. There are four different types of this disease. For more information about Gaucher disease visit Answers.com
Golgi apparatus
Polycystic disease is a congenital defect in which one or both of the kidneys have numerous large cysts.
lysosomal enzymes